Is there any evidence that CoQ10 works? (2024)

Is there any evidence that CoQ10 works?

Several clinical studies suggests that CoQ10 supplements help reduce swelling in the legs; reduce fluid in the lungs, making breathing easier; and increase exercise capacity in people with heart failure. But not all studies are positive, and some found no effect, so using CoQ10 for heart failure remains controversial.

Is CoQ10 really worth taking?

CoQ10 supplements might be beneficial for treating conditions such as congestive heart failure and preventing migraines. CoQ10 is considered safe, with few side effects. However, be sure to take this supplement under your doctor's supervision.

What do cardiologists say about CoQ10?

Coenzyme Q10, also known as CoQ10, is a substance that helps generate energy in your cells. Your body makes CoQ10 naturally, but its production tends to decrease with age. Many cardiologists recommend CoQ10 supplements, especially for patients with heart conditions.

What is the new research on CoQ10?

Supplementation with CoQ10 significantly reduced the relative risk of both cardiac-related deaths (43%) and all-cause mortality (42%). There was no significant difference in adverse events between the CoQ10-treated and placebo groups over the duration of the study.

What happens when you take CoQ10 everyday?

Coenzyme Q10 (CoQ10) has been linked to improved aging, exercise performance, heart health, diabetes, fertility and migraines. It may also counteract adverse effects of statin medications. Typically, 90–200 mg of CoQ10 per day are recommended, though some conditions may require higher dosages of 300–600 mg.

Is there any downside to taking CoQ10?

While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can cause allergic skin rashes in some people. It also might lower blood pressure, so check your blood pressure carefully if you have very low blood pressure.

What vitamin should not be taken with CoQ10?

Be aware that beta-sitosterol is also used at a much higher dose for lowering cholesterol (by competing with cholesterol for absorption in the gut) and, at this higher dose, you would not want to take it at the same time you take the fat-soluble supplements -- vitamin D and CoQ10, both of which are best taken with a ...

Which is better for heart CoQ10 or fish oil?

CoQ10 acts directly on heart muscle cells to enhance function. Fish oil provides indirect heart protection by improving risk factors. The evidence for blood pressure reduction is stronger for fish oil than CoQ10. CoQ10 requires higher daily doses for effects, while fish oil benefits often seen at under 1,000 mg/day.

What are the symptoms of needing CoQ10?

Other neurological abnormalities that can occur in primary coenzyme Q10 deficiency include seizures, intellectual disability, poor muscle tone (hypotonia), involuntary muscle contractions (dystonia), progressive muscle stiffness (spasticity), abnormal eye movements (nystagmus), vision loss caused by degeneration ( ...

Which CoQ10 is the most effective?

Is there something better than CoQ10?

Ubiquinol is the form your body actually uses to achieve its benefits. Substantial research shows that if you are over 25, this reduced form is superior for your health in a number of ways. You should take ubiquinol every day for its superior bioavailability and far-ranging health benefits.

Why does CoQ10 make me feel so good?

In particular, research suggests that it may help improve heart health and blood sugar regulation, protect against certain types of cancer, and reduce the frequency of migraine. It may also reduce oxidative damage that leads to muscle fatigue, skin damage, and brain and lung diseases.

What is more powerful than CoQ10?

Astaxanthin outperforms CoQ10 800 times over in fighting free radicals. CoQ10 has a wide variety of health benefits, including heart health, skin health, fertility, exercise performance, and cognitive function.

Is it better to take CoQ10 at night or in the morning?

There's no standard guideline for the best time to take CoQ10. However, the general rec is to take CoQ10 in the morning with a meal, due to its potential energizing effects. * But like all supplements, CoQ10 isn't one-size-fits-all—so it's possible that a later-in-the-day dose might work for you.

What foods are high in CoQ10?

Primary dietary sources of CoQ10 include oily fish (such as salmon and tuna), organ meats (such as liver), and whole grains. Most individuals obtain sufficient amounts of CoQ10 through a balanced diet, but supplementation may be useful for individuals with particular health conditions.

Can I take CoQ10 with vitamin D?

Interactions between your drugs

No interactions were found between CoQ10 and Vitamin D3.

Is CoQ10 hard on the liver?

In addition to reducing the risk of cardiovascular problems in patients with liver disease, CoQ10 supplementation may also benefit the disease process within the liver by reducing inflammation and oxidative stress.

Does CoQ10 help with anxiety?

After evaluating the effect of CoQ₁₀ on the psychopathological symptoms, a clinically significant improvement was observed in all subscores from SCL-90-R, being statistically significant for the reduction in interpersonal sensitivity (P < 0.001), depression (P < 0.001), anxiety (P < 0.001), hostility (P < 0.001), and ...

Does CoQ10 help with joint pain?

Many cardiologists place their patients on CoQ10 to help cardiac function as well as to reduce the bad side effects of statin cholesterol drugs. The supplement also may help decrease the pain of rheumatoid arthritis by decreasing the bad inflammatory chemicals that lead to cartilage breakdown.

Is CoQ10 hard on kidneys?

Chronic Kidney Disease (CKD)

There is evidence that CoQ10 supplementation may improve renal function and reduce the need for dialysis in patients with CKD.

Does CoQ10 interact with coffee?

No interactions were found between caffeine and CoQ10.

Does CoQ10 lower cholesterol?

The pooled analysis revealed that CoQ10 supplementation significantly reduced total cholesterol (TC) (MD -5.53 mg/dL; 95% CI -8.40, -2.66; I2 = 70%), low-density lipoprotein cholesterol (LDL-C) (MD -3.03 mg/dL; 95% CI -5.25, -0.81; I2 = 54%), and triglycerides (TGs) (MD -9.06 mg/dL; 95% CI -14.04, -4.08; I2 = 65%) and ...

Is it OK to take fish oil and CoQ10 together?

CoQ10 is stored in the mitochondria—your cell's power source—where one of its primary functions is to generate energy for the cells. Because your body's natural production of CoQ10 tends to decrease as you age, combining CoQ10 with pure fish oil helps your body absorb and use CoQ10 better!

Do heart doctors recommend CoQ10?

Overall, CoQ10 was found to be safe, to improve symptoms, and to reduce major adverse cardiovascular events. A meta-analysis of studies on congestive heart failure also demonstrated increased exercise capacity and reduced mortality with CoQ10 intake.

What is the preferred form of CoQ10?

The best CoQ10 supplements use ubiquinol, which research suggests is a more effectively absorbed form of CoQ10 than ubiquinone; these two are the most common forms of coenzyme Q10 supplements. Because CoQ10 is oil soluble, you'll also benefit from consuming it alongside dietary fat to ensure good absorption.